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課程名稱 |
近代腫瘤生物學特論Ⅰ
Modern Tumor Biology Ⅰ |
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開課學期 |
101-1 |
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授課對象 |
醫學院 腫瘤醫學研究所 |
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授課教師 |
何蓓茵 |
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課號 |
Onco8013 |
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課程識別碼 |
453 D0140 |
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班次 |
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學分 |
2 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期五3,4(10:20~12:10) |
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上課地點 |
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備註 |
本課程中文授課,使用英文教科書。上課地點：基因體5樓教室。腫瘤醫學研究所博士班必選修課程。與郭遠燁、張純榮、陳美齡、歐大諒合開
限博士班
總人數上限：20人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
THIS COURSE IS DESIGNED TO BE AN INTRODUCTORY COURSE FOR THOSE WHO ARE INTERESTED IN UNDERSTANDING ONCOGENESIS. THE COURSE WILL COVER SEVERAL ISSUES INCLUDING EPIGENETICS, TUMOR ANGIOGENESIS, IMMUNOSURVEILLANCE, IMMUNE ESCAPE AND INFLAMMATION IN THE PROCESS OF MALIGNANT TRANSFORMATION. SOME MATERIALS, LIKE CELL CYCLE AND CHEMICAL CARCINOGENESIS, WILL NOT BE EXPLAINED IN FULL DETAIL BUT WILL BE REVIEWED BRIEFLY. THOSE WHO HAVE TAKEN ONE BASIC COURSE IN TUMOR BIOLOGY AND GRADUATE STUDENTS FROM NON-ONCOLOGY BACKGROUNDS ARE WELCOME. |
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課程目標 |
N/A |
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課程要求 |
N/A |
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預期每週課後學習時數 |
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Office Hours |
每週五 10:00~12:00 |
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指定閱讀 |
N/A |
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參考書目 |
1. JOHN, M., PETER, M. H., MARK, A. I., JOE, W. G., & CRAIG, B. T.(2008). THE MOLECULAR BASIS OF CANCER. PHILADELPHIA: SAUNDERS ELSEVIER.
2. Robert A. Weinberg. (2007). The Biology Of Cancer, Garland Science. |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
9/14 |
Introduction
Cancer: a genetic disorder
Hallmarks of cancer |
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第2週 |
9/21 |
Oncogenes |
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第3週 |
9/28 |
Tumor suppressor genes
Genetic mouse models of cancer |
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第4週 |
10/05 |
DNA repair pathways and human cancer |
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第5週 |
10/12 |
Signal transduction by growth factor receptors |
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第6週 |
10/19 |
Cellular immortalization, multi-step tumorigenesis, and the evolution of cancer |
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第7週 |
10/26 |
Epigenetics and cancer |
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第8週 |
11/02 |
Infectious agents and cancer |
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第9週 |
11/09 |
Mutagenes, carcinogens, mutations and environmental carcinogenesis |
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第10週 |
11/16 |
期中考 |
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第11週 |
11/23 |
Cancer stem cells
Cell growth |
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第12週 |
11/30 |
Apoptosis, autophagy, and necrosis |
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第13週 |
12/07 |
The tumor microenvironment in cancer progression and tumor-promoting stimuli |
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第14週 |
12/14 |
Cellular senescence
Tumor angiogenesis |
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第15週 |
12/21 |
Regulation of the cell cycle
Invasion and metastasis |
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第16週 |
12/28 |
Imaging and cancer |
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第17週 |
1/04 |
Metabolism of cell growth and proliferation
Cancer genomics |
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第18週 |
1/11 |
期末考 |
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